From the new interview in Sight & Sound, where Lynch says he can now only direct remotely:
"I've gotten emphysema from smoking for so long, & so I'm homebound whether I like it or not. I can't go out. And I can only walk a short distance before I'm out of oxygen... And now because of Covid, it would be very bad for me to get sick, even with a cold. So I probably would be directing from my house. And because of Covid, they've now invented ways where you can direct from home. I wouldn't like that so much. I like to be there amongst the thing & get ideas there. But I would try to do it remotely, if it comes to it."
He is asked whether his 2010 screenplay ANTELOPE DON'T RUN NO MORE will ever get produced. "Well, we don't know what the future will bring... but we remain hopeful."
It's an interesting interview. A somewhat more lighthearted bit: "[A] lot of times I watch crime shows at night. I like to think & watch TV at the same time. I've seen many Forensic Files [1996-2011]. I've seen probably all of them, but I like to see them over and over again. And apparently, so do other people; they're like friends. It's really fun to watch these crime shows - a lot of studies in human nature, and then the horrible things that humans can do to one another; it's amazing. And the fantastic scientists and detectives who uncover the killers."